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Contents |
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Mini Models: Aquaporin, Potassium Channel, Green Flourescent Protein, Zinc Finger
Consumer Product Safety Warnings
States of Water Tattoo Set
Water Kit© and NaCl Lattice
Hemoglobin Nylon Model
Mini-Toober ß-Globin Folding Kit©
Sidechain Upgrade Kit
Sidechain Plus Maps Upgrade Kit
ß-Globin Mini Model
Amino Acid Starter Kit©
Sidechain Upgrade Kit
Sidechain plus Circle Upgrade Kit
Amino Acid Starter Kit© Poster
Science Olympiad 2012 Protein Modeling Event
2012 Prebuild Kits
2012 Practice Kits
3DMD Genetic Codon Wall Chart
Amino Acid Building Block Models
Hemagglutinin Mini Model
Insulin Poster
Insulin mRNA to Proteins Kit© 3DMD Paper BioInformatics Activity & Mini-Toober Folding Kit ©
Insulin Mini Model
Custom Mini-Toober Folding Kits
Molecules of Life Collection©
Nucleosome Mini Model
DNA Discovery Kit©
DNA Starter Kit© Pilot Study Version
Map of Human ß-Globin Gene© 3DMD Paper BioInformatics Activity
ß-Globin Mini Model
DNA Mini Model
70s Ribosome Mini Model
Large and Small Ribosome Mini Models
Large Ribosome Mini Model
Small Ribosome Mini Model
Transfer RNA Mini Models
Nylon tRNA Model
David Goodsell Cellular Landscapes
Immunoglobulin Fold & Antibody (Plaster & Nylon) Mini Models
Acetylcholinesterase Active Site Cube
Anthrax and Hemolysin Mini Models
Modeling Toobers
Product Order Form
Replacement Items
DNA Discovery Kit©
Water Kit© and NaCl Lattice
Amino Acid Starter Kit©
Mini-Toober ß-Globin Folding Kit©
Map of the Human ß-Globin Gene©
Individual Items
Payment and Shipping (found on page 16 of the Product Order Form)
Custom Models (web exclusive)
BioMolecular Explorer CD (web exclusive)
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Aquaporin Mini Model 3.75" Plaster Model (AQUAMM) |
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Aquaporin — a membrane-spanning protein — is responsible for moving
water across a lipid bilayer. Its structure consists of 7 alpha helices that form an
hour-glass shape through which water molecules move, one at a time. Two asparagine amino acids are
strategically positioned at the narrowest point of the hour-glass and provide selectivity to this channel —
only water molecules pass through. Aquaporin was discovered by Peter Agre in 1996. He was awarded the
Nobel Prize in Chemisry in 2003 for this work, along with Roderick MacKinnon, who characterized the
structure of the potassium channel. For more information about water channels, see Dr. Agre’s Nobel
address at http://nobelprize.org/. Mini Models are made of plaster by rapid prototyping and should be
handled with care. Meets National Science Education Standards. |
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Potassium Channel Mini Model 3.75" Plaster Model (PCMM) |
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The potassium channel is a 4-subunit, trans-membrane protein that allows the rapid passage of potassium ions —
but not sodium ions — across the membrane. The protein backbones of the 4 subunits come together to form a
channel, with carbonyl oxygen atoms precisely positioned in 3-D space to replace the water that normally
hydrates each ion. Since there is no energetic difference between a hydrated potassium ion and the same ion
bound in the pore of the potassium channel, the ion rapidly passes through the channel in a frictionless manner.
This potassium channel protein structure was determined by Roderick MacKinnon in 1998. He was awarded the
Nobel Prize in Chemistry in 2003 for this work, along with Peter Agre, who characterized the structure of
aquaporin, the water transporter. Mini Models are made of plaster by rapid prototyping and should be handled
with care. Meets National Science Education Standards. |
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Green Fluorescent Protein Mini Model 3" Plaster Model (GFPMM) |
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Green Fluorescent Protein (GFP) is reponsible for the green bioluminescence of many marine organisms,
including the Pacific Northwest Jellyfish. Its structure consists of an 11-stranded beta-barrel surrounding a central
alpha-helix containing the fl uorophore that emits light. The backbone is color-coded for students to follow the
folding of the protein from its amino- to its carboxy-terminus. It is an excellent tool when teaching protein
structure and/or biotechnology. It also can be used with the Amino Acid Starter Kit©. Mini Models are made of
plaster by rapid prototyping and should be handled with care. Meets National Science Education Standards.
Find out more |
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Zinc Finger Mini Model 3.5" Plaster Model (ZFMM) |
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A zinc finger is a short (~30 amino acid) protein motif that is often found in proteins that bind to DNA.
Zif268 is a DNA binding protein that contains 3 consecutive zinc fi ngers. Proteins with zinc fingers are one
of the largest families of proteins found in the human genome. Each zinc finger consists of a two-stranded
beta-sheet and a short alpha-helix. Its structure is stabilized by 2 cysteines and 2 histidines that bind to a
single zinc atom. Mini Models are made of plaster by rapid prototyping and should be handled with care. Meets National Science Education Standards. |
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Consumer Product Safety Warnings |
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3D Molecular Designs utilizes magnets in many products to help students understand the inter- and intra-molecular forces in the molecular world. In compliance with the Consumer Product Safety Improvement Act of 2008, 3DMD adds the warnings below to our products and encourages the safe use of our products in classrooms and other science education settings. Please contact us if you have questions or concerns. |
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WARNING: SMALL MAGNETS |
This product contains small magnets. Swallowed magnets can stick together across intestines causing serious infections and death. Seek immediate medical attention if magnets are swallowed or inhaled. |
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WARNING: CHOKING HAZARD |
This product contains small parts and should be kept out of the reach of children under the age of 3, because the parts or their pieces may present a choking hazard to small children. |
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This is a science education product, not a toy. It is not intended for children under 8 years old. |
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States of Water Tattoo Set (SWTS) |
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With these fun Water Tattoos, you can simultaneously reward your students and reinforce the concepts related to the three states of water. Each set contains 50 Water Vapor Tattoos, 50 Liquid Water Tattoos and 50 Frozen Water Tattoos. |
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Water Kits© (WK-01, WK-02, WK-06) |
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Each Water Kit© cup includes pieces for 12 water molecules,
1 sodium, 1 chloride, 1 ethane, and 1 hydroxyl group. All atoms are
magnetized to refl ect their positive or negative charges (except for non-polar ethane).
Your students can make ice, dissolve salt, evaporate water, explore transpiration, create
ethanol, and much, much more! CD with lesson plans and activitities included in each kit.
Molecules are packaged unassembled. Meets National Science Education Standards. Project Lead the Way® selected the Water Kit© for its BioMedical Sciences™ Program.
Find out more.
Water Kit Basic Lesson Plans
Water Kit© Resource Pages
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NaCl Lattice (NACL-03, NACL-04) |
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Your students can discover the cubic nature of salt crystals,
effi cient lattice packing, high melting temperature, brittleness,
cleavage planes, and more with these models. Each ion model
has 6 embedded magnets to simulate ionic bonding. The 4x4x4
Lattice contains 64 ions (32 sodium and 32 chloride) and the
3x3x3 Lattice contains 27 ions (13 of 1 type of ion and 14 of
the other.) Lattices do not include 3DMD Water Molecules©.
Water Molecules are sold in Water Kits© (see water kit above).
Meets National Science Education Standards
NaCl Resource Pages
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Hemoglobin Nylon Model (NHGM) |
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If you could have only one model with which
to teach proteins, this is it – a durable, hand-painted
nylon model of hemoglobin. One of the ß-Globin chains is
magnet-docked on the rest of the quaternary complex which includes the two α-chains and a
second ß-chain, so it can be removed to examine closely. The heme group and its oxygen on
the removable ß-globin are also magnet-docked. The glutamic acid sidechain at position six of
the ß-globin chain can be exchanged for a valine sidechain – representing the change in the ßglobin
protein that leads to sickle cell anemia. This nylon model is made on a rapid prototyping
machine – not mass produced. It is more resilient than plaster models, but will break if abused. |
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Mini-Toober ß-Globin Folding Kit© (MTBGMU, MTBGFKU) |
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Proteins become real in your students’ hands as they fold 3 Mini-Toober ß-Globin fragments
and discover the primary, secondary and tertiary structure in this model. Maps guide your
students in folding the Mini-Toobers into ß-Globin’s 3-D shape. This Kit is the next step in
helping your students understand proteins, after engaging in the Amino Acid Starter
Kit©activities. The Mini-Toober ß-Globin Folding Kit© includes Mini-Toobers, folding map
guides, amino acid sidechains, heme group, iron atom, oxygen atoms, and an assortment of
parts to mark and connect the fragments. The Folding Kit can be used successfully by 6 to 9
students working in 3 teams. Meets National Science Education Standards. Project Lead the Way® selected the ß-Globin Folding Kit© for its BioMedical Sciences™ Program.
Improved Sidechains
These dynamic, accurate new sidechain models feature embedded magnets in a durable plastic. Customers who previously purchased the ß-Globin Folding Kit© can upgrade their kits, see below. Proof of purchase from 3D Molecular Designs or Project Lead The Way required. |
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ß-Globin Folding Kit© Sidechain Upgrade (MTBGFK-R-Sidechain Upgrade Kit) |
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Upgrade your ß-Globin Folding Kits©
1 Complete Set of Sidechains, Heme Group, Oxygen and Iron Atoms
1 Set of Metal Mini-Toober Clips (16 total)
1 Sheet of Property Coding Labels and White Dot Labels
3 Sidechain List Charts
1 CD with Teacher Notes, Student Handouts and Jmol Visualization Tools |
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ß-Globin Folding Kit© Sidechain Upgrade Plus Maps (MTBGFK-R-Sidechain plus Maps Upgrade) |
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Upgrade your ß-Globin Folding Kits©
1 Set of Folding Maps (Red, Blue and Green)
1 Complete Set of Sidechains, Heme Group, Oxygen and Iron Atoms
1 Set of Metal Mini-Toober Clips (16 total)
1 Sheet of Property Coding Labels and White Dot Labels
3 Sidechain List Charts
1 CD with Teacher Notes, Student Handouts and Jmol Visualization Tools
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ß-Globin Mini Model 4" Plaster Model (BGMMFK) |
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ß-Globin is a small protein (146 amino acids) that transports oxygen throughout our bodies. This model
features the heme group with its iron atom which binds oxygen, the location of the sickle cell mutation, and
selected charged, hydrophobic and hydrophilic sidechains. The model is useful in teaching both physiology
and protein structure. This Mini Model can be used as an accurate smaller scale template when using the Mini-
Toober ß-Globin Folding Kit©. Mini Models are made of plaster by rapid prototyping and should be handled with
care.
Meets National Science Education Standards.
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Amino Acid Starter Kit© (AASKU-01, AASKU-03, AASKU-06) |
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(3 Group Set Shown)
Your students explore the primary, secondary and tertiary structure of
proteins with the captivating models and tools in this dynamic kit. They
learn the chemical properties of the 20 amino acid sidechains through a
dual coloring scheme — a colored band at the base of each sidechain
indicates chemical properties while embedded colored balls in the
model show atomic structure. Understanding protein structure begins
with this unique combination of structure and chemical properties of
the amino acid sidechains. Through the kit’s engaging hands-on
activities your students gain a basic knowledge of protein folding. Then
they discover the importance of secondary structure with an additional
folding activity.
Each 1-Group Set includes 1 magnetic chemical properties circle,
1 amino acid sidechain list, 22 amino acids, 1 4-foot Mini-Toober, 15
metal clips and 6 hydrogen bond connectors. Multiply each item by 3, 5
or 6 for the 3-Group, 5-Group and 6-Group sets.
Teacher notes, student handouts and interactive Jmol visualization tools
available online. Meets National Science Education Standards.
Project Lead the Way® selected the Amino Acid Starter Kit© for its BioMedical Sciences™ Program.
New Old |
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Improved Sidechains
These dynamic, accurate new sidechain models feature embedded magnets in a durable plastic. Customers who previously purchased the Amino Acid Starter Kit© can upgrade their kits. Proof of purchase from 3D Molecular Designs, Carolina Biologicals or Project Lead The Way required. |
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AASK Sidechain Upgrade Kit (AASK-R-Sidechain Upgrade) |
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Upgrade your Amino Acid Starter Kits©
1 Set of Upgraded Magnetic Plastic Amino Acid Sidechains (22 total)
1 Set of Metal Mini-Toober Clips (15 total)
1 Sheet of Property Coding Labels
1 CD with Teacher Notes, Student Handouts and Jmol Visualization Tools
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AASK Sidechain plus Circle Upgrade Kit (AASK-R-Sidechain & Circle Upgrade) |
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Upgrade your Amino Acid Starter Kits©
1 Set of Upgraded Magnetic Plastic Amino Acid Sidechians (22 total)
1 Set of Metal Mini-Toober Clips (15 total)
1 Sheet of Property Coding Labels
1 CD with Teacher Notes, Student Handouts and Jmol Visualization Tools
1 Magnetic Chemical Properties Circle
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Amino Acid Starter Kit© Poster (AASKP) |
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The Amino Acid Sidechain Poster allows students to connect the chemical structure of each amino acid sidechain – as it is commonly represented in text books – with the physical models of each sidechain supplied in the Amino Acid Starter Kit.
The poster features a dual color scheme. First, each atom of the sidechain is color coded according to atom type (red for oxygen, blue for nitrogen, gray for carbon and yellow for sulfur). Second, the base of each sidechain is color-coded to reflect the overall chemical property of the sidechain (yellow for hydrophobic sidechains, red for acidic sidechains, blue for basic sidechains and white for hydrophilic but uncharged sidechains and green for cysteines). |
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2012 Prebuild Kits, Science Olympiad Protein Modeling Event |
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This is the kit to order to provide the basic materials to construct your Prebuild Caspase-3 models for regional, invitational, state, and national competitions including 2 Mini-Toobers, Endcaps and Support Posts.
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2012 Practice Kits,
Science Olympiad Protein Modeling Event (SOP12) |
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Now your students can practice for the Science Olympiad’s new Protein Modeling Event by using these practice kits.
The 2012 Practice Kit is based on the 2011 State Onsite build of NANOG.
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3DMD Genetic Codon Wall Chart 24" x 30" (GCWC) |
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The 3DMD Genetic Codon Wall Chart can be used in conjunction with 3DMD’s
popular Amino Acid Starter Kit© and ß-Globin Folding Kit© — which introduce
your students to a standard color scheme: hydrophobic amino acids are yellow,
polar amino acids are white, acidic amino acids are red and basic amino acids
are blue. By applying this same color scheme to the Codon Chart, your students
can easily build a seamless connection between the triplet codon in mRNA and
the chemical property of the amino acid it encodes. |
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Amino Acid Building Block Models (AABB) |
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These Amino Acids Building Block Models enable your students to explore the basic structure of amino
acids – the building blocks of proteins. The Kit contains all of the atoms and bonds needed to construct two
models of a generic amino acid. Sidechains are represented by the pink spheres. The two amino acids can be
joined by a peptide bond to make a dipeptide – splitting out a water molecule. 3D Molecular Designs and
Molymod have teamed up to make this kit available to our customers. Activities for using the models are
posted online.
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Hemagglutinin Mini Model 6.5" Plaster Model (HAMM) |
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The hemagglutinin protein (HA) of the infl uenza virus plays a critical role in the infection process. These models
show the dramatically different shapes of the hemagglutinin HA2 protein at pH 7 and at pH 5. These models will
allow you to tell an amazing molecular story – of how the virus takes advantage of the dramatic decrease in pH
following the uptake of the virus by receptor-mediated endocytosis. Models magnet-dock on to the base and can be
removed for closer examination. Color coding enables students to clearly see the conformational changes that the
protein undergoes.
This model can also be used in conjunction with the Tour of the Human Cell Panorama on page 11. The Human
Cell Panorama illustrates a ß-cell that has been stimulated to produce antibodies in response to the flu vaccine.
Mini Models are made of plaster by rapid prototyping and should be handled with care. Meets National Science Education Standards.
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A 3DMD Paper BioInformatics Activity & Mini-Toober Folding Kit ©
Insulin mRNA to Protein Kit© |
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BioInformatics and
Folding Activity: 3DMD’s
new mRNA to Protein Kit© helps your students understand that the specific sequence of amino acids in a
protein is encoded by the specifi c sequence of nucleotides in the corresponding
gene. After using the BioInformatics Map to search for the nucleotide sequence
that encodes the amino acid sequence of insulin, your students will fold a
physical model of the 3-D structure of the insulin protein, using Mini-Toobers
(1 for the A-Chain and 1 for the B-Chain) using a folding map.
Each 1-Group Set includes student mRNA map, student folding map, 2 Mini-
Toobers, sidechains, metal clips, support posts, endcaps, and an assortment of
parts to mark and connect the chains. Multiply each item by 3 or 6 for the
3-Group and 6-Group sets. Each set also includes 1 Teacher mRNA
map and CD with directions and Jmol visualization tools.
Poster: By using the insulin protein as a starting point, teachers can weave
together a broad range of biology topics including the flow of genetic
information, biochemistry and protein structure, cellular organelles, anatomy,
physiology and cell biology of glucose homeostasis, energy metabolism, the
endocrine and digestive systems, recombinant DNA technologies, and new
approaches to monitor blood glucose levels and control diabetes. 
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Insulin Mini Model 4" Plaster Model (IFKMM) |
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This alpha carbon backbone model of insulin, a 51-amino acid peptide hormone, features 2 chains (A is orange
and B is purple) joined by two disulfi de bonds. This model is useful in teaching basic principles of protein structure
– including quaternary structure. The insulin model can also be used in conjunction with the Insulin mRNA
to Protein Kit© (above). Mini Models are made of plaster by rapid prototyping and should be handled with care. Meets National Science Education Standards. |
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Custom Mini-Toober Folding Kits (Contact us for a quote) |
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You or your students select the structure and choose the sidechains you want to feature. Send your
specifications to us and we will customize a Mini-Toober Folding Kit for you. This is a great opportunity
for college instructors to match a model to their course or use the model as an assessment tool. High school
teachers can do the same in advanced level courses or use it as a special project for advanced students. Allow
1 week for quoting and 1 to 4 weeks for us to assemble and package your Custom Mini-Toober Model Kits.
Kit contents, number of kits and time of year will affect price and processing time.
Prices vary according to length of Mini-Toobers, number of sidechains and other parts. Contact us for a quote. |
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Molecules of Life Collection© |
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The Molecules of Life Collection© features
plaster models of the four major types of
biomolecules — DNA, proteins, lipids and
complex carbohydrates. Since the biomolecules
exist and interact in an aqueous environment,
water is also included. An associated model of
a monomer building block goes with each
biomolecule. A major teaching point is that
large complex biomolecules are made of
small, simple monomer units.
The models sit on a 24” x 19” placemat that
includes a description of each structure.
The entire set includes 12 models:
DNA, adenosine monophosphate, ß-globin,
histidine, cell membrane, phospholipid, starch,
glycogen, cellulose, glucose, ice structure,
water molecule and placemat. All models are
built to the same scale — 20 million times
their real size. The models are
made of plaster by rapid
prototyping and should be
handled with care. Meets National Science Education Standards.
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Nucleosome Mini Model 4" Plaster Model (NCSMM) |
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The nucleosome is the most basic, repeating structural unit of chromosomes. Its central protein core has 8
histones (2 copies each of H2A, H2B, H3 and H4) and 145 base pairs of double-stranded DNA. The N-terminal
end of each histone has many positively-charged amino acids that interact with the negatively-charged phosphate
backbone of DNA. This model reveals that histones interact only with the minor groove of DNA. The major
groove is then available for sequence-specifi c DNA binding proteins, such as Zif 268 (see Zinc Finger Mini
Model, page 2). Mini Models are made of plaster by rapid prototyping and should be handled with care. Meets National Science Education Standards. |
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| DNA Discovery Kit© (DNA-02, DNA-12) |

Let your students discover the structure of DNA — just as Watson and Crick did.
The DNA Discovery Kit© combines magnets with accurate 3-D nucleotides which
make the kit self-instructive. As your students discover AT and GC base pairs, they will
feel the hydrogen bonding. Teacher-developed and fi eld-tested, the 12 Base Pair Set contains 6 AT and 6 GC base
pairs, display stand, 2 Mini-Toobers and CD with extensive activities, materials and background information.
The 2 Base Pair Set includes 1 AT and 1 GC base pair, and CD. Meets National Science Education Standards
Project Lead the Way® selected the DNA Discovery Kit© for its BioMedical Sciences™ Program.
More Photos
DNA Resources
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Pilot Study Version
DNA Starter Kit© (DNASK-02, DNASK-01) |
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Your students will immediately become engaged with this friendly, interactive, foam model of double-stranded DNA and single-stranded RNA. The DNA Starter Kit© is a schematic model that transforms from the familiar ladder shape to the double helix with a twist. Your students can explore the structure of color-coded DNA bases showing purines and pyrimidines which connect to a continuous sugar-phosphate backbone. Then they can delve into replication and transcription. Using individual nucleotide triphosphates they can synthesize a new strand of DNA – one base at a time -- showing the semi-conservative replication of DNA. Finally they can synthesize mRNA – one base at a time— to show the process of transcription.
Teachers who participate in the Pilot Study will provide valuable information that will help determine final configuration of kits for middle school, high school and college-level instruction.
Each one-group set includes 54 bases (12 red adenine, 12 yellow thymine, 12 blue cytosine, 12 green guanine, 3 white uracil), 4 continuous gray backbones, 24 gray sugar-phosphates, 12 lavender sugar-phosphates and 48 orange phosphates.
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A 3DMD Paper BioInformatics Activity
Map of the Human ß-Globin Gene© |
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Don’t just tell your students about triplet codons, reading frames, or introns and exons. Let
them discover these eukaryotic gene features as they explore the Map of the Human ß-Globin
Gene©. Starting with the protein sequence, students work backward to discover the ß-Globin
Gene. Student maps can be used by individuals or small groups and are available in sets
of 1, 3 or 12. Student sets do not include the CD.
The Teacher’s Map features highlighted reading frames and mutation sites. The CD includes
Teachers’ Notes, instructions, and student handout. All maps are laminated. Meets National Science Education Standards.
Project Lead the Way® selected the Map of the Human ß-Globin Gene© for its BioMedical Sciences™ Program. |
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ß-Globin Mini Model 4" Plaster Model (BGMMPBI) |
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This ß-Globin Mini Model is designed to use with the Map of the Human ß-Globin Gene© (above). The 3 colors of
its alpha carbon backbone correspond to the 3 exons in the gene. Selected sidechains on the model indicate
mutations that are noted on the Teacher Map of the Human ß-Globin Gene©. The model also features the heme
group with its iron atom binding oxygen. It is useful in teaching physiology and protein structure, as well as
bioinformatics. Mini Models are made of plaster by rapid prototyping and should be handled with care. Meets National Science Education Standards. |
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DNA Mini Model 8" Plaster Model with Base (DNA4FMM) |
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This model immediately engages your students in thinking about the structure of DNA. You can guide a discussion of the nature
of models — and the usefulness of multiple representations of any molecular structure. The DNA Mini Model represents the
classic DNA double helix in 4 formats. The bottom section of the model shows a surface format emphasizing major and minor
grooves. Moving up, all atoms are in a CPK colored spacefi lled format. The next section shows the 4 nitrogenous bases in a
CPK wireframe format. In the top section of the model each of the 4 bases is colored with a solid color. Mini Models are made
of plaster by rapid prototyping and should be handled with care. Meets National Science Education Standards. |
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70S Ribosome Mini Model 4" Plaster Model (R70SMM) |
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This model shows the two subunits of the bacterial ribosome (30S
and 50S) assembled into the functional 70S ribosome. In an assembled
ribosome with the small and large (70S) subunits bound together, the 3’-ends of the
tRNA are immediately adjacent to the catalytic adenosine in the large subunit. The physical
models of the individual 30S and the 50S subunits (below) cannot be assembled into the 70S complex,
due to the static nature of the physical models. Mini Models are made of plaster by rapid prototyping and
should be handled with care. Meets National Science Education Standards
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Large and Small Ribosome Mini Models 4" Plaster Models (R5030SMM) |
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Venkatraman Ramakrishnan, Thomas A. Steitz and Ada E. Yonath won the Nobel Prize in Chemistry in 2009 for studies of the structure and function of the ribosome! http://nobelprize.org/
Protein synthesis becomes understandable as your students see the 3 tRNAs of the small (30S) subunit
and how they fi t into the cavity of the large (50S) subunit to synthesize proteins. In the large subunit, they
will see the single adenosine base (yellow) that catalyzes peptide bond formation during protein synthesis.
The large subunit of a bacterial ribosome is a protein-RNA complex composed of 34 proteins and 2
rRNAs (23S and 5S). The rRNA folds into this specific 3-D structure, with the proteins serving as the
mortar between RNAs. The newly synthesized protein exits the ribosome through a visible channel that
extends from the catalytic adenosine to the surface of the ribosome.
The small subunit of the bacterial ribosome is a protein-rRNA complex composed of 21 proteins and a
single RNA (16S). It folds into a specifi c 3-D structure and is stabilized by associated proteins. In this
spacefi lled model, two tRNAs (green) dock with their 3’-ends close together – ready for peptide bond
formation.
Mini Models are made of plaster by rapid prototyping and should be handled with care. Meets National Science Education Standards. |
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Small (30S) Ribosome Mini Model 4" Plaster Model (R30SMM) |
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30S Ribosome
(also available as a pair) |
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Large (50S) Ribosome Mini Model 4" Plaster Model (R50SMM) |
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50S Ribosome
(also available as a pair) |
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Transfer RNA Mini Models 3.5" Plaster Model (TRNAMM) |
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Transfer RNA (tRNA) is a short RNA molecule (76 nucleotides) that delivers amino acids to the ribosome,
where they join to a growing chain during protein synthesis. Transfer RNAs fold into 3-D structures, stabilized
by hydrogen bonding between complementary bases. In this model, the phosphate backbone of the tRNA is
white, the 4 bases are red, the anticodon is blue, and the 3’-end (where the amino acid is bound) is yellow.
Mini Models are made of plaster by rapid prototyping and should be handled with care. Meets National Science Education Standards. |
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Nylon tRNA 3" Nylon Model (NTRNAM) |
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RNA folds into complex 3D shapes – just like proteins. This nylon model of tRNA shows the details of this
complex 3D structure – complete with the AT and GC base-pairs that stabilize the structure. The model allows
students to explore the anti-codon of the tRNA, and the 3' end of tRNA where the charged amino acid is added.
This nylon model is made on a rapid prototyping machine – not mass produced. It is fragile and will break if
abused. Meets National Science Education Standards. |
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David Goodsell Cellular Landscapes |
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(Mitochondria Poster) |
David Goodsell, PhD, scientist, author and artist of all things small, creates
landscapes that accurately illustrate the size, shape, and distribution of proteins in
their natural environment of the cell. These unique images connect the molecular world,
inferred by X-ray crystallography and NMR spectroscopy, with the cellular world, observed by light and
electron microscopy.
These laminated prints of Goodsell’s stunning water color paintings illustrate biology in a dimension not seen in
other instructional tools. Adjacent text identifi es the proteins and explains their functions. Whether teaching the
flow of genetic information, the many jobs of proteins, energy metabolism or the immunology of a flu shot,
these landscapes may be the missing piece in your current collection of instructional tools. Meets National Science Education Standards.
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(Tour of a Human Cell Panorama) |
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Immunoglobulin Fold Mini Model 3.25" Plaster IgG Fold (IGGMM) |
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The immunoglobulin (IgG) fold consists of a 4-stranded beta-sheet — opposite a
3-stranded beta-sheet — joined by a disulfi de bond. This highly successful protein
fold is found in many proteins, especially those that function in our immune system.
Models are made of plaster or nylon on rapid prototyping machines – not mass produced. They should be handled with care. The nylon model is more resilient than the plaster models, but will break if abused. Meets National Science Education Standards. |
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Antibody Mini Model (available in 3.25'' plaster or 4.25'' nylon) |
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Antibodies are composed of 12 immunoglobulin folds; 4 in each heavy chain
(yellow in the model) and 2 in each light chain (red in the model). The antigen
binding site of an antibody is composed of the ends of two immunoglobulin folds (1
yellow heavy chain and 1 red light chain) that are positioned at the tips of the Yshaped
antibody. With this model, teachers can introduce students to concepts of
protein structure and function while teaching the immune system.
Models are made of plaster or nylon on rapid prototyping machines – not mass
produced. They should be handled with care. The nylon model is more resilient than
the plaster models, but will break if abused. Meets National Science Education Standards. |
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Acetylcholinesterase Active Site Cube© 5" Plaster Cube Model (ACHASC) |
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Now your students can unfold an enzyme to see how the
precisely positioned active site amino acids bind to specifi c
substrates to catalyze a reaction. As your students unfold the
active site cube they will see how the tightly-packed amino
acid sidechains bind the substrate (acetylcholine) and discover
how 3 amino acids collaborate to cleave the neurotransmitter.
Your students will explore how an insecticide targets the
enzyme in mosquitoes and see what happens when a mutation
blocks the insecticide from binding to the enzyme. This has
led to the emergence of insecticide-resistant mosquitoes. The
substrate, insecticide and mutant amino acid sidechain bind to
the enzyme with magnets. The models are made of plaster by
rapid prototyping and should be handled with care. Meets National Science Education Standards. |
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Anthrax Protective Antigen Mini Model 3.25" Plaster Model (ATXMM) |
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Seven subunits of the anthrax protective antigen protein assemble into a ring that embeds itself in the membrane
of a cell, which allows 2 additional anthrax toxin proteins — lethal factor and edema factor — to enter the cell. In
this model, each subunit is color-coded according to 4 different protein domains. White represents a dominant negative inhibitor. This is a mutant form of the protein that assembles into a heptamer. It is unable, in this form, to
allow the transport of the other 2 anthrax toxin proteins into the cell. Mini Models are made of plaster by rapid
prototyping and should be handled with care. Meets National Science Education Standards. |
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Hemolysin Mini Model 3.5" Plaster Model (HLNMM) |
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Hemolysin is a protein of Staphylococcus aureus. Like the anthrax protective antigen heptamer (above), 7
subunits of hemolysin assemble into a complex that embeds itself into the membrane of a red blood cell. Each
subunit of the heptamer contributes two-strands to a 14-stranded beta-barrel that is inserted into the membrane
to create a hole. Hemoglobin protein then leaks out of the red blood cells, making the iron available to the
bacteria to support their growth. Mini Models are made of plaster by rapid prototyping and should be handled
with care. Meets National Science Education Standards. |
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Modeling Toobers 4' Toober (TBR-01) |
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Versatile Modeling Toobers provide hands-on learning experiences in many science disciplines.
Biology and chemistry students can model DNA or create protein structures while following the
principles of chemistry. Physics students can explore sound and other waves. The flexible foam
Toobers have a soft wire core and are 4’ long. Push Pins Not Included. Find out more.
15 Tack and a 4 Foot Toober (pdf)
Meets National Science Education Standards |
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Custom Models |
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 3D Molecular Designs is happy to estimate the cost of a model that is customized to meet your research or education needs. Receive a custom model price quote. |
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BioMolecular Explorer 3D (BECD) |
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3D Molecules on CD for High School Biology BioMolecular Explorer 3D (BME3D) is a collection of 3D-interactive, biologically significant molecules relevant to a high school biology curriculum. Windows software is provided on the CD. (Mac users, see the online version of BME3D. Classic or OS9 required.)
BME3D provides easy access to interactive 3D structures of biologically significant molecules without needing to connect to the Internet, and without requiring a great deal of technical expertise. All molecules included on the Biomolecular Explorer 3D CD are displayed and explored in a browser window following software installation. The price of the CD covers the media, production and handling costs-- software and other materials are free, thanks to support from the National Science Foundation, and MDL, Inc.
The BME3D CD includes:
- software for Windows (Mac users see below)
- step-by-step instructions
- 10 pre-selected molecules with descriptions to place them in context: DNA, antibody, HIV protease with inhibitor, hemoglobin, a lipid bilayer, collagen, lactase, lac repressor, myosin, water.
- links to online lesson planning resources for each molecule
- links to more molecules online
To preview the contents of the CD, visit BME3D online! If you have stable internet access in your classroom, you can use all BME3D materials from BME3D online, without getting the CD.
Software for Macs (Classic or OS9 required) is available only at the BME3D online web site. |
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| Replacement Items |
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Replacement parts available to customers who previously purchased kits: Proof of purchase required from 3D Molecular Designs, Project Lead the Way, Carolina Biological Supply Company, Science Kit, Flinn Scientific or other distributor. Please contact us for information: 414-774-6562 or contactus3dmd@3dmoleculardesigns.com
DNA Discovery Kit©
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Water Kit© and NaCl Lattice
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Amino Acid Starter Kit©
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Mini-Toober ß-Globin Folding Kit©
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Map of the Human ß-Globin Gene©
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Individual Items
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