
CRISPR
This CRISPR-Cas9 model communicates the structure and function of the Cas9 protein currently being used to edit animal and plant genomes. It was produced for the Innovative Genomics Institute (IGI) and Dr. Jennifer Doudna, recipient of the 2020 Nobel Prize in chemistry. The Cas9 protein (white) is shown in surface format and the guide RNA (orange) and target DNA (blue) are shown in spacefill format.
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CRISPR
This CRISPR-Cas9 model communicates the structure and function of the Cas9 protein currently being used to edit animal and plant genomes. It was produced for use by Dr. Jennifer Doudna, recipient of the 2020 Nobel Prize in chemistry, in a series of public lectures including a TED Talk. The Cas9 protein (white) is shown in surface format and the guide RNA (orange) and target DNA (blue) are shown in spacefill format.
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CRISPR
This CRISPR-Cas9 model communicates how the various domains of the Cas9 protein (white) can bind to a guide RNA (orange) and cut double-stranded DNA (blue). The model uses embedded magnets that allow components to detach and be assembled in a variety of ways, demonstrating the dynamic nature of the Cas9 protein.
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CRISPR
This CRISPR-Cas12f1 model communicates the structure and function of the Cas12f1 protein. The protein domains (white and gray) are shown in surface format and the guide RNA (orange) and target DNA (blue) are shown in spacefill format. The components are held together with embedded magnets to allow for disassembly. The model also attaches to a removable display base complete with custom text plaque.
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CRISPR
This CRISPR-Cas9 model communicates the complex domain structure of the Cas9 protein. The path of the protein chain (rainbow gradient) interacts intricately with the guide RNA (pink) and target DNA (white and gray). Key nucleotides such as the PAM sequence (green) and cut sites (magenta) are also highlighted.
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CRISPR
This CRISPR-Cas9 model communicates the structure of the nucleotides to be held in place by the Cas9 protein. The guide RNA (orange) is shown bound the target strand of DNA (dark blue). The non-target strand of DNA (light blue) is shown separating from the target strand. Embedded magnets allow the model to further disassemble, demonstrating a double-stranded cut in the DNA segment.
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CRISPR
This CRISPR-Cas9 model communicates the structure and function of the Cas9 protein. It was designed to compliment dynamic Cas9 animations produced by John Liebler and his scientific animation company Art of the Cell. The Cas9 protein (tan) is shown in surface format and the guide RNA and target DNA (green and blue) are shown in spacefill format.
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