Viruses
This large adeno-associated virus model communicates the overall pentameric structure of the virus capsid. Each of the 60x protein monomers (colored red, yellow, green and blue by radius distance from the center of the virus) are shown in alpha carbon backbone display format. One full pentamer comprised of 5x monomers has embedded magnets that allow it to be separated, revealing the interior geometry of the capsid.
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Viruses
This poliovirus model was designed for Vincent Racaniello, host of the popular “This Week in Virology” (TWIV) video blog. It communicates the overall structure of the virus (purple) as well as the structure and binding orientation of the poliovirus receptor (blue). Embedded magnets allowed the virus model to separate into two halves and attach to a display base with custom text plaque.
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Viruses
This coronavirus model communicates the overall structure of the SARS-CoV-2 virus and how it docks on a host cell. The viral membrane (gray), viral spike proteins (red), host cell membrane (green) and ACE2 receptor protein (green) are shown in surface display format. Embedded magnets allow the virus to detach from the host cell and open to reveal the viral genome (green).
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Viruses
This coronavirus model was developed in collaboration with Brookhaven National Labs to communicate SARS-CoV-2 research to lab visitors, including the Governor of New York State, Kathy Hochul. It shows the viral membrane (gray), spike proteins (red), and host cell membrane (white) in surface display format and uses embedded magnets to disassemble and attach to the custom display base.
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Viruses
This hepatitis virus model communicates the overall multi-chain nature of the virus capsid along with several proteins that bind to the virus. The capsid is colored by chain (green, cyan, yellow and magenta) and is shown in surface display format. The binding proteins (orange and green) are shown in ribbon display format and have embedded magnets that allow them to dock onto the capsid.
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Viruses
This collection of adeno-associated virus models were designed to celebrate the research accomplishments of the Perelman School of Medicine’s Gene Therapy Program. The virus is shown in surface display format and colored by radius distance from the center point of the virus capsid. Embedded magnets attach each virus to a custom display base, which then sits inside a plexiglass display case.
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Viruses
This pair of models communicate the structure of the influenza virus and its primary surface protein, hemagglutinin. The model on the left shows a full flu virus in surface display format, including the viral membrane (yellow), the hemagglutinin proteins (purple) and the neuraminidase proteins (pink). The model on the right shows an enlarged hemagglutinin protein in alpha carbon backbone format.
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Viruses
This HIV protease model communicates the overall homodimer structure of the protein (orange and blue) with select key sidechains shown in the active site and binding sites (colored by element). Embedded magnets allow the protein chains to separate into individual parts.
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Viruses
This large spike protein model communicates the overall trimeric nature of the SARS-CoV-2 spike protein (yellow, magenta and cyan), along with the structure of an inhibitor protein (orange) that binds simultaneously to all three chains of the spike protein. The inhibitor has embedded magnets that allow it to separate from the spike protein trimer.
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