Genome Editing I Webinar

CRISPR - As an Adaptive Immune System in Bacteria

Tim Herman, PhD, Director, Center for BioMolecular Modeling Explore CRIPSR as an adaptive immunity system in bacteria using the new Adaptive Immunity Kit^©. A classic 2012 paper proves how this system works and will give your students practice in interpreting scientific data. Model how restriction enzymes connect to a CRISPR endonuclease for editing the human genome.

CRISPR: It’s All about Yogurt

Tim Herman, PhD, Director, Center for BioMolecular Modeling Discuss the classic paper from 2012 that definitively proved how the adaptive immunity system works and use this paper with your students to practice interpreting scientific data with a connection to current biological research.

Session Resources

• Adaptive Immunity Presentation Slides PDF
• Adaptive Immunity Presentation Slides PowerPoint
• Could You Have Discovered CRISPR? Slides PDF
• Could You Have Discovered CRISPR? Slides PowerPoint
• CRISPR Adaptive Immunity System 3-Step Guiding Graphics
• CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes Article
• Microbial Warfare Against Viruses Article

Use the foam nucleotides from the Nucleotide Student Modeling Pack^© for the CRISPR restriction enzymes activity Tim models in the video below. Please refer to the handouts below the video.

• Comparing CRISPR-Cas9 and a Restriction Enzyme
• Activity Cas9 cuts a Statistically Unique Sequence in the Human Genome

3D Molecular Designs' Products

• CRISPR Adaptive Immunity Kit^©
• CRISPR-Cas9 Mini Model^©

Free 3D Molecular Designs' Resources

• CRISPR Adaptive Immunity Kit^© Resources
• CRISPR-Cas9 Mini Model^© Resources