Making the Cut with CRISPR-Cas9©
Product Code: MCC
$88
Cutting edge science becomes accessible for your students as they engage Cas9 into action.
⚠ Warning
Description
Your students have heard about CRISPR, now, they can model how this protein can modify DNA. With Making the Cut with CRISPR-Cas9©’s colorful foam pieces and placemat your students can build an interactive model of the CRISPR-Cas9 RNA-guided endonuclease, including the viral double-stranded DNA and dual guide RNA. You can observe students transferring their prior knowledge of DNA structure while modeling how the Cas9 protein functions.
- Build a schematic model of the CRISPR-Cas9 RNA-guided endonuclease, including the viral double-stranded DNA and dual guide RNA
- Understand how the Cas9 protein binds to a specific sequence of viral double-stranded DNA at a PAM site - and cuts it
- Demonstrate how that cut destroys the viral genome and prevents the infection of bacteria
- Amplify their learning with student handouts and digital materials
Content & Assembly Instructions
1-Group Set Content
1 Foldable Placemat*
6 White sticky-back Cas9 parts
2 White Nuclease parts
5 Orange tracr RNA pieces
1 Black Spacer RNA piece
40 Red Adenine (A) DNA Nucleotides
40 Yellow Thymine (T) DNA Nucleotides
40 Green Guanine (G) DNA Nucleotides
40 Blue Cytosine (C) DNA Nucleotides
40 Purple RNA Nucleotides (10 each of A, U, G & C)
40 Tan RNA Nucleotides (10 each of A, U, G & C)
40 Blue RNA Nucleotides (10 each of A, U, G & C)
1 Gray Tetraloop
1 Gray Cytosine Deanimase
*Placemat may be folded in half (printing out) before applying the sticky-back foam to make storage in the box easier. Or leave the placemat flat and store outside of box. See Assembly Instructions for more information.
Making the Cut with CRISPR-Cas9© 1-Group Set Contents
