ß-Globin Folding Kit©

Product Code: BGFK


Quantity: - +

One kit is all you need to engage three teams of up to 6 students each in collaboration about the molecular cause of sickle cell anemia.

⚠  Warning


Reveal the molecular relationship between structure and function, protein synthesis, and mutation as you tell classic stories in biology. Oxygen transport and how it can be disrupted becomes real in your students’ hands as they:

  • Interpret folding maps to form the primary structure of the protein with mini toobers
  • Fold 3 mini toobers into alpha helices and then their tertiary structures
  • Assemble the three fragments together to form ß-globin
  • Add the heme group with an iron atom and O2
You can create an authentic application activity as students predict the impact of a single-point mutation on the function of the protein. This kit is most effective after students have explored the Amino Acid Starter Kit©.

ß-Globin Folding Kit©
Mini Toobers (red, green, and blue)3
Laminated Folding Maps3
Bags with Parts (blue, green, red, and yellow)4
Amino Acid Side Chains
Heme Group and Heme Connectors
Plastic Clips
Support Posts
Colored Dots
Laminated Amino Acid Side Chain Charts©3
Wooden Dowels3

ß-Globin Folding Kit© Description, Set-Up and Contents with Plastic Clips

ß-Globin Folding Kit© Description, Set-Up and Contents with Metal Clips & Magnets

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